Regenerative Medicine

Liposuction is now applied to harvest autologous adipose-derived regenerative cells in regenerative medicine.

What is Regenerative Medicine?

Regenerative medicine itself isn’t new — the first bone marrow and solid-organ transplants were done decades ago. Recent advances in developmental and cell biology, immunology, and other fields have unlocked new opportunities to refine existing regenerative therapies and develop new ones.

Stem Cells from Body Fat

Stem cells extracted from body fat (using liposuction) may pave the way for the development of new regenerative therapies including soft tissue reconstruction following tumor removal or breast mastectomy surgery, the development of tissue-engineered cartilage or bone, and the treatment of cardiovascular disease.

Adipose tissue (fat cells) is also one of the richest sources of Mesenchymal cells or MSCs. These are the cells that can differentiate into a variety of cell types including bone cells, cartilage, and connective tissues but they also have tremendous cellular activity and release potent growth factors.

The advantages include less ethical controversy, abundant cell availability from discarded tissues from elective surgeries like breast reductions, Smart Liposuction, and tummy tucks, and a much-reduced possibility for immune rejection when re-implanting cells extracted from a person’s own fat.

Stromal Vascular Fraction using Liposuction

Recent advances in stem cell science have made it possible to obtain high numbers of quality multi-potent cells from a person’s own fat, harvested by liposuction.

SVF is a state-of-the-art technology where a patient’s own adipose-derived stem cells are used to heal his or her body. Fat is processed to yield up to 500 times the number of adult mesenchymal stem cells (per cc of fat) than can be yielded from bone marrow or blood. The procedure entails performing a mini-liposuction (around 50 mL of fat tissue) typically from the abdomen, under local anesthesia. Stem cells are extracted from the tissue, are then incubated and deployed within ninety minutes or less. These stem cells are activated and administered back into the patient where they secrete growth factors, thus leading to their regenerative potential.

What are the possible treatments?

All cells in our body are constantly dividing to form new cells. Eventually these cells will age and die. Stem cells are your body’s natural healing cells and can act as the repair system in your body by regenerating the cells that make up tissues.

Orthopedics

Millions of people around the world suffer from pain caused by conditions such as arthritis, traumatic injury, and other degenerative disorders related to age or overuse.

Traditionally, treatment options for these painful and debilitating conditions include surgery which can be costly, invasive, and require painful lengths of downtime. Patients often claim that the affected areas or joints never return to their original healthy state of mobility and ease of use even after surgery. Alternatives exist for those who want to avoid surgery, such as steroid injections and temporary cartilage substitutes or lubrication agents. However, these types of treatments provide only temporary relief, and repeated use can actually damage surrounding tissues over time.

Stem cells and progenitor cells are human cells with the potential to regenerate many different cell types in the body. They help in recruiting new cells in existing healthy tissues, which then repair injured or damaged areas. Our advanced orthopedic stem cell therapy uses precise injections of your own stem cells, under the premise that these cells secrete local growth factors to recruit new cells to help the body heal damaged muscles, ligaments, tendons, cartilage, bones, and spinal discs. This non-surgical stem cell injection procedure usually happens within a day and offers the hope of an alternative to surgery and joint replacement.

Anti Aging

PRP has a long history of being used in orthopedic medicine, dentistry,
and reconstructive surgery. Now this technology is being applied to reverse signs of aging, scarring, and sun damage.

With the use of PRP and cell based therapies, we have the ability to perform
image-enhancing procedures such as face and breast lifts. When injected into affected areas of skin, these therapies can stimulate collagen production and tissue regeneration. These procedures can help reduce wrinkles,
improve skin tone and texture, and give life to faces that look drawn, tired, and aged.

Hair Restoration

For well over a decade, our doctors have been safely, strategically, and effectively fighting the root causes of hair loss while educating both men and women on how they can achieve natural-looking results by harnessing the power of their own cells.

Your stem cells are your body’s natural healing cells and can act as the repair system in your body by replenishing adult tissues. There are three accessible sources of autologous adult stem cells in humans: bone marrow, blood, and adipose tissue (fat).

Of all stem cell types, autologous harvesting (meaning the cells are obtained from one’s own body) from adipose (fat) tissue involves the least risk. Adipose tissue can yield more than 500 times the amount of stem cells per gram of fat when compared to aspirated bone marrow.

Sexual Wellness

Up to 30 percent of men and 40 percent of women may experience some type of sexual dysfunction.

For many couples, intimacy is not always enjoyable. Recent studies have shown biocellular therapy to be a viable option for sexual therapy treatments. If you or your partner could use some help in the bedroom, PRP and stem cell therapy might be the answer.

The O-Stem Protocol is a revolutionary introduction of Platelet Rich Plasma (PRP) therapy for female intimate wellness. The O-Stem Protocol serves a similar purpose and follows a similar protocol as the O-Shot®, and is one of the only treatments available for female sexual dysfunction.

The P-Stem Protocol is a Platelet Rich Plasma (PRP) therapy for penis rejuvenation combined with AMLI (autologous lipocyte micronized injection) and stem cells that can help men with enhancement of erection, sensitivity and penis size. This simple, relatively painless in-office procedure uses blood-derived growth factors to rejuvenate the penis, improving functionality and boosting sensation. Similar to the P-Shot®, the P-Stem Protocol uses materials from your own body, and is injected directly into the affected area.

Frequently Asked Questions

What diseases and problems can be treated?
This will depend on the type of degenerative condition you have. A specialist will evaluate you and discuss your candidacy for stem cell therapy. After you have a complete understanding of the potential risks and benefits for your recommended treatment and would like to explore this avenue of treatment, you can be considered for our cellular therapies. Of course, even though it’s a minimally invasive procedure, you will still need to be medically cleared to participate in the procedure.
Does Regenerative Medicine use embryonic stem cells?
No. Only adult mesenchymal stem cells are used. These cells are capable of forming bone, cartilage, fat, muscle, ligaments, blood vessels, and certain organs. Embryonic stem cells are associated with ethical considerations and limitations. Recent advances in stem cell science have made it possible to obtain high numbers of quality multi-potent (able to form numerous other tissues) cells from a person’s own liposuction fat. We use state-of-the-art technology to process this fat to yield approximately five hundred thousand to one million stem cells per cc of fat, and therefore, it is possible to obtain as many as 10 to 40 million cells from a single treatment.
How are the cells deployed into a patient?
Theoretically, depending on the type of treatment required, stem cells can be injected through veins, arteries, into spinal fluid, subcutaneously, or directly into joints or organs. We however have taken precaution to research only the safest methods which include local deployment into a joint or tissue, or IV through a filter. Stem cells injected intravenously are known to “seek out and find” areas of tissue damage and migrate to that location thus potentially providing regenerative healing. Intravenously injected stem cells have also been shown to have the ability to cross the “blood-brain barrier” to enter the central nervous system and they can be identified in the patient’s body many months after deployment. More research is needed however to fully understand the systemic action of these cells.
How many injections are required for success?
It has been reported that many patients, especially those with orthopedic conditions, require only one deployment for years of relief. Certain types of degenerative conditions, particularly autoimmune disease, may respond best to a series of stem cell deployments. The answers to timing and dosing are still considerations and areas for more research.
Are any biological agents or growth factors added to the stem cells?
Our adipose derived stem cell harvesting and isolation technique yields exceedingly high numbers of stem cells. In reviewing outcomes data, treatment cell numbers appear to correlate with treatment success. Our cells are actually in a type of “soup” called Stromal Vascular Fraction (SVF), which are stem cells bathed in a rich mixture of natural growth factors. Some indications appear to respond better to stem cells that are super-enriched with growth factors created by administering Platelet Rich Plasma (PRP) to the patient. PRP is derived from a patient’s own blood. No foreign substances or medications are added to the stem cells.
Why do patients request stem cell treatments?
Many patients have been told that they require surgery or other risky treatments for their ailments and are looking for non-invasive options. Patients may have heard compelling testimonials about stem cells in the media or on various websites. We does not make exaggerated claims since our work is still investigational, but we are a resource for patients who would benefit from access to regenerative care. We give you a choice to those informed patients who seek modern regenerative therapies.
What is the cost of consultation and treatment?
Patients who are considered to be candidates based on information provided in the candidate application form will be invited for a consultation with one of our physicians. Unfortunately, insurance generally will not cover the actual cost of stem cell treatment since stem cell therapy is still in the investigational stages. The cost varies depending on the disease state being treated and which type of stem cell deployment is required.
What is included in the procedure cost?
Because of recent innovations in technology, we are able to provide outpatient stem cell treatment at a fraction of the cost of that seen in many overseas clinics. Our fees cover Stromal Vascular Fraction SVF harvesting, preparation, and deployment, which may include the use of advanced interventional radiology and fluoroscopy techniques.
How long until I can expect to see improvement?
Different conditions are treated in different ways and there are different degrees of success. If the goal is regeneration of joint cartilage, one may not see expected results until several months after treatment. Some patients may not experience significant improvement and others may see dramatic regeneration of damaged tissue or resolution of disease. The regenerative process takes time, particularly with orthopedic patients, who may not see results for several months. In some diseases, more immediate responses are possible.