Comparisons between Xeomin, Dysport, and Botox


Many adults seek to improve the appearance of their skin to prevent wrinkles, fine lines, and crow’s feet. In the rapidly advancing and constantly changing world of medicine, there are more options than ever to help keep skin looking younger longer, without looking “plastic” or fake. Some of these options include things like Xeomin (Incobotulinumtoxin A), Dysport (Abobutlinumtoxin A), and Botox (Onabotulinumtoxin A).

While these types of injections and plastic surgeries used to be only accessible to Hollywood personalities, but this is far from the case today. These are various types of treatment available to “average” the average person like never before. Each also has its benefits and advantages based on the results you are looking for.

Xeomin (Incobulinumtoxin A):

Xeomin is an injection that was approved by the FDA in 2015 to treat adults with muscle stiffness in the upper limbs including conditions such as Cervical Dystonia and Blepharospasm. This treatment has begun to replace Botox for these types of conditions. Similar to Botox, Xeomin is injected into the muscle that is in spasm.

Xeomin is primarily used to treat stiff muscles in the upper limbs. For adults with Spasticity of the Upper Limbs, abnormal positioning of the head or neck pain, in adults with Cervical Dystonia, and in abnormal spasms of the eyelids in adults with Blepharospasms. Medical results are generally seen within 7 days of receiving the injections, but this may vary from patient to patient.

Xeomin has often been proven to help people with moderate to severe frown lines, especially those between the eyebrows. Many patients who use Xeomin to reduce fine lines have an improvement of about 2 points within 30 days of starting treatment. Results may vary for each individual. These results are based on clinical studies and the average effect among patients.

Xeomin works the same way for both Upper Limb Stiffness (ULS) and frown lines. Xeomin injections are made through a unique process that isolates the therapeutic components of the injection and removes the “accessory proteins” that cause muscles to contract so people with ULS and those with frown lines also experience relief .

Dysport (Abobotulinumtoxin A):

Dysport (Abobutulinumtoxin A) is another FDA-approved option for injections to help prevent the effects of wrinkles, frowns, and aging. Unlike Xeomin, Dysport is not used to treat ULPs, but rather to treat wrinkles, frowns, and general symptoms of aging. This is a recommended treatment for those under 65, those seeking anti-aging injections.

Dysport is the botulinum neurotoxin called Abobotulinumtoxin A, which acts as a blocking agent to help prevent frequent and specific small muscle contractions that cause deep frown lines and are used between the brow lines, and are a sterile single use of 300 road units. This means that Dysport imposes about 2.5 times the amount of medication to be effective as Botox. This dose is equivalent to about 50 injections per treatment distributed among all the muscle groups involved. Most patients experience noticeable improvement in moderate to severe frown lines improving within 2-3 days after treatment.

While a Dysport treatment takes around 50 injections, the good news is that the average dose of Dysport lasts around 16 weeks (4 months) versus 12 weeks (3 months) for Xeomin. In the end, Dysport saves the patient one treatment a year, so the convenience of going one less time can be an advantage.

Botox (Onabotulinum toxin A):

Cosmetic Botox is the oldest FDA-approved of the three drugs, having received its FDA approval in 2002. It is the most common of the three drugs used to reduce wrinkles, frown lines, and crow’s feet; It has been administered more than 10.6 million times since it was put on the market in 2002. It is also available in more than 78 other countries. The main reason why Botox is the most widely used of the three medications is that it has been on the market as an FDA-approved treatment much longer than Xeomin and Dysport.

Botox treatments should be repeated once every 12 weeks (3 months) to maintain maximum results, which is similar to how Xeomin should be administered. Each treatment requires about 20 injections per treatment. It’s also worth noting that between 1997 and 2014 the number of men receiving Botox treatment has increased by 273%, and men now account for around 10% of all Botox treatments performed.

Side Effects of Botulinum Family Drug Procedures:

Xeomin, Dysport, and Botox are all from the botulinum family of drugs, which can have some rare but serious side effects when used in people with special or pre-existing conditions or sensitivities. The most common side effects to watch out for are trouble swallowing, speaking, or breathing. This is due to the weakening of associated muscles in the face from the effect of botulinum-based drugs. If the muscles overreact to the injections it can cause these serious complications.

There are also rare cases of toxins spreading throughout the body that can cause loss of strength, muscle weakness, double vision, and hoarseness/total loss of voice after receiving any medication within the botulinum family.
Rare cases of allergies to the ingredients of the various drugs of the botulinum family have also been reported. If you have allergies to any ingredients in the injections, do not use this treatment. Swelling at the injection site is the most common sign of allergic reactions to the drug being used. Do not drive a motor vehicle, operate machinery, or participate in dangerous activities without knowing how you will react to these injections.

Also, make sure that all procedures are performed by a certified plastic surgeon or specialist. People who perform these procedures without proper training will surely be cheaper, but the process often goes terribly wrong, and the person performing the procedure often has no idea how to fix what has gone wrong. You will be left with a shoddy job, and possibly permanent damage to the area that was treated. It’s worth the extra money to make sure you find someone who can do quality work, and won’t cause permanent damage in the process.

Also, before starting any new treatment regimen, talk to your doctor to make sure the treatment is right for your personal needs.


Xeomin, Dysport, and Botox are very similar in many ways, as they are all designed to temporarily relax the muscle groups that are responsible for wrinkles, frown lines, and crow’s feet. However, some differences remain. The biggest difference is that Xeomin is only approved to treat upper extremity spasticity. Both Xeomin and Botox are recommended to be taken every 12 weeks (3 months), while Dysport can be taken every 16 weeks (4 months).

However, Dysport requires around 50 injections per treatment, where Xeomin and Botox only require 10-25 injections depending on the size of the muscle area being injected. In the end, Dysport typically requires about 25% fewer treatment sessions than Xeomin or Botox as treatments are only needed 3 times a year vs. 4 times a year for Xeomin or Botox. Xeomin takes about 7 days, and sometimes up to 30 days until the skin looks its best. With both Dysport and Botox patients typically see full results much faster, usually within 2-3 days.

It’s also worth noting that all three treatments are considered “safe” by FDA standards. Also, no matter what treatment is chosen these are considered cosmetic treatments. This means that most insurance companies will not pay for the treatment, and it is up to the client to pay the full cost of the treatment. Companies often offer treatment discounts to entice clients to try their product for the first time, or offer discounts for booking multiple procedures at once. This can help you save money.

Xeomin, Dysport and Botox are considered viable options to help reduce the wrinkles, frown lines and crow’s feet that you are looking to disappear. Neither of these procedures is likely to get rid of those lines completely, but they can help fade them. Results will also vary depending on the patient. Talk to your doctor today to see which option is best for you!